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HelpEpic Test Code LAB101011 NeoComplete Paraneoplastic Evaluation with Recombx®
Additional Codes
Athena Code: 4620
Type of Disorder
Paraneoplastic and Other Antibody Disorders of the CNS
Disease(s) Tested for:
Paraneoplastic Neurological Syndrome
Indications for Testing
Acute or subacute onset of the symptoms mentioned above or otherwise unexplained neurological syndromes
Specimen Type
Serum
Preferred Container
Red Top
Minimum Volume
2 mL
Storage Requirements
Refrigerate if not shipped same day. Serum is stable up to 3 days
Specimen Stability
Room temperature: 72 hours
Refrigerated: 21 days
Frozen: 28 days
Transportation Needs
Room Temperature, avoid freezing. Ship same day.
Reference Values
Please see individual test listings
Includes
Test Turnaround
| 7-10 days |
Clinical Significance
Anti-Hu, anti-CV2, anti-Yo, anti-Ri, anti-CAR, anti-Ma, anti-Ta, anti-Zic4 antibodies, anti-voltage gated calcium channels (VGCC), anti-P/Q type and voltage gated potassium channels (VGKC), anti- Ganglionic AChR, anti-Amphiphysin, anti-NMDA receptor (NR1-subunit), anti-LGI1, anti-CASPR2, and anti-GAD65 are found in patients with the acute or subacute onset of limbic encephalitis, brainstem encephalitis, focal cortical encephalitis, myelitis, cerebellar degeneration, opsoclonus/myoclonus, retinopathy, sensory neuropathy, autonomic dysfunction, Stiff Person Syndrome and/or Lambert-Eaton Myasthenic Syndrome. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases.
Methodology
Automated Nanoliter Scale Immunoassay, ELISA, Radioimmunoassay, Immunofluorescence Assay (IFA)
CPT Code
86255(3), 86341(1), 83519(3), 83520(8)
Last Updated
21-OCT-20