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Epic Test Code LAB103 Magnesium: Serum

Performing Location(s)

BMC,CRH,LFH,HRK,OCH,FTT,FOX,FCC

Specimen Type

Serum or Plasma

Preferred Container

Gold or Red top tube

Alternate Container

Green top tube

Minimum Volume to Submit for Testing

0.5 mL Serum or Plasma

  • Multiple test can be performed from this volume. For question please contact the lab at 547-3975.  

Storage Requirements

Sample tubes should be centrifuged within 2 hours of collection 

Gold tops are stable in original tubes for 7 days DO NOT ALIQUOT

Aliquot Red tops

See Causes of Rejection for temperature requirements.

Transportation Needs

 Deliver specimen to laboratory within 1 hour of collection if unspun. If not possible see "storage Requirements". 

Causes for Rejection

Mislabeled or unlabeled specimen
Less than 50% draw for Vacutainer tubes
> 7 days refrigerated
> 24 hours room temperature
Hemolysis > 150 mg/dL HgB
Lipemia > 500 mg/dL Trig
Bilirubin > 36 mg/dL Bili
EDTA, NaF

Reference Values

Population

Units

Reference  Range

Low Critical Value

High Critical Value

All populations except Inpt. OB

mg/dL

1.9-2.7

<1.0

>4.0

Inpt. OB only

mg/dL

5.0-8.0

<1.0

>8.0

 

Additional Information

Contraindications:

Studies have shown that gadodiamide containing contrast media used in Magnetic Resonance Imaging (MRI) can produce analytic interference, both positive and negative, with assays performed in the clinical Laboratory for Calcium, Iron Magnesium, TIBC and Zinc. The package insert for Gadodiamide recommends waiting 12 to 24 hours between contrast agent administration and blood specimen collection to ensure that the contrast agent has been cleared. A longer waiting period might be necessary for patients with renal insufficiency. The average half-life of gadodiamide in patients with severely reduced renal function is 34 hours.

Inpatient OB patients administered MgSO₄ to prevent development of preeclampsia have a different therapeutic range and critical value from other patients (see ranges below).

Limitations

Because magnesium is three times more concentrated in erythrocytes than in serum, hemolyzed samples will give spuriously elevated results

 

Lipemia with triglyceride of 600 mg/dL [6.86 mmol/L] and bilirubin of 20 mg/dL [342 µmol/L] decreases the MG result by 0.6 mg/dL [0.25 mmol/L] and 1.0 mg/dL [17 mmol/L] respectively at a magnesium concentration of 1.8 mg/dL [0.74 mmol/L].

 

Lipemia with triglyceride of 600 mg/dL [6.86 mmol/L] does not affect the MG result (<0.1 mg/dL) [<0.05 mmol/L] at a magnesium concentration of approximately 2.0 mg/dL [0.82 mmol/L].

 

Capillary collected blood may differ from venous due to contamination from hemolysis or interstitial fluid.

Days of Analysis

All

Available STAT

Yes

Methodology

Beckman AU/Dx Series

CPT Code

83735

Last Updated

26-OCT-24 MS