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Epic Test Code LAB1077 Protein Electrophoresis with Reflex to Immunofixation Electrophoresis Monoclonal Protein Detection, Quantitation & Characterization, IgA, IgG, & IgM, Serum

Additional Codes

ARUP:2002109

Performing Location(s)

ARUP

Ordering Recommendation

Aids in the diagnosis and management of multiple myeloma and related disorders when clinical pretest probability is low. Use to detect and quantify monoclonal serum protein.

Specimen Type

Serum

Preferred Container

Gold top tube

Blood Tube Draw Volume

Min 50% draw volume  

Minumum Volume to Submit for Testing

1.5 mL Serum

Specimen Stability

Ambient: Unacceptable
Refrigerated: 1 week
Frozen: 1 month 

Storage Requirements

Refrigerated.

Transportation Needs

Refrigerated.

Causes for Rejection

Mislabeled or unlabeled specimen.
Less than 50% draw for Vacutainer tubes
Plasma

Specimens transported ambient

Reference Ranges

Components Reference Interval
Albumin 3.75-5.01 g/dL
Alpha 1 Globulin 0.19-0.46 g/dL
Alpha 2 Globulin 0.48-1.05 g/dL
Beta Globulin 0.48-1.10 g/dL
Gamma 0.62-1.51 g/dL
Total Protein, Serum Refer to report. Reference intervals may vary based on instrumentation.
Monoclonal Protein ≤0.00 g/dL

 

Interpretive Data

Immunofixation electrophoresis is a more sensitive technique than serum protein electrophoresis for the identification of small M-proteins found in patients with amyloidosis, early or treated myeloma and macroglobulinemia, MGUS, solitary plasmacytoma, and extramedullary plasmacytoma.

Reflex Testing

If patterns from serum protein electrophoresis are monoclonal or suspicious, then Immunofixation Electrophoresis will be added. Additional charges apply.

IFE is a more sensitive method for determining and defining monoclonal proteins. No additional testing will be added for proteins that are normal, polyclonal, or that lack monoclonal patterns.

Turnaround Time

1-5 days once recived into performing lab

Days of Analysis

Sun-Sat

Available STAT

No

Methodolgy

Quantitative Capillary Electrophoresis/Qualitative Immunofixation Electrophoresis/Quantitative Immunoturbidimetry/Colorimetry

CPT Code

84155; 84165; if reflexed, add 82784 x3; 86334

Last Updated

20-FEB-24 MS