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Mayo Clinic Laboratories

Epic Test Code LAB119 Protein Electrophoresis, Serum

Additional Codes

ARUP:0050640

Performing Location(s)

ARUP

Ordering Recommendation 

Detects and quantifies monoclonal protein (M-protein) in serum. Use in screening and monitoring of multiple myeloma and related disorders.

Specimen Type

Serum

Preferred Container

Gold top tube

Minimum Volume

1 mL serum

Specimen Stability

Refrigerated: 1 week
Frozen: 1 month

Ambient: Unacceptable

Storage Requirements

Refrigerated

Transportation Needs

Refrigerated

Causes for Rejection

Mislabeled or unlabeled specimen.
Less than 50% draw for Vacutainer tubes
Plasma

Specimen kept at ambient temperature

Reference Ranges

Components

Reference Interval

Total Protein-Electrophoresis

6.00-8.30 g/dL

Albumin

3.75-5.01 g/dL

Alpha 1 Globulin

0.19-0.46 g/dL

Alpha 2 Globulin

0.48-1.05 g/dL

Beta Globulin

0.48-1.10 g/dL

Gamma

0.62-1.51 g/dL

Monoclonal Protein ≤0.00 g/dL

Interpretive Data

Serum protein electrophoresis, when used as a screening test, is useful in the detection of various pathophysiologic states such as inflammation, protein loss, gammopathies, and other dysproteinemias. However, immunofixation electrophoresis (IFE) is a more sensitive technique for the identification of small M-proteins found in patients with amyloidosis, early or treated myeloma or macroglobulinemia, solitary plasmacytoma, or extramedullary plasmacytoma.

Turnaround Time

1-3 days once received into performing lab

Days of Analysis

Sun-Sat

Available STAT

No

Methodolgy

Quantitative Capillary Electrophoresis/Colorimetry

CPT Code

84155;84165

Last Updated

20-FEB-24 MS