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HelpEpic Test Code LAB12306 Iodine, Serum
Additional Codes
MML:IOD
Reporting Name
Iodine, SUseful For
Determining iodine overload using serum specimens
Monitoring iodine levels in individuals taking iodine-containing drugs
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Patient Preparation:
1. Disinfectants (such as Betadine) that contain iodine should not be used during venipuncture.
2. High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies:
-Metal Free B-D Tube (No Additive), 6 mL (T184)
-Metal Free Specimen Vial (T173)
Collection Container/Tube: Plain, royal blue-top Vacutainer plastic trace element blood collection tube
Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial
Specimen Volume: 1 mL
Collection Instructions:
1. Allow specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction.
2. Remove the stopper. Carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
3. See Trace Metals Analysis Specimen Collection and Transport for complete instructions.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Ambient | 21 days | ||
| Frozen | 21 days |
Special Instructions
Reference Values
40-92 ng/mL
Day(s) Performed
Tuesday, Friday
CPT Code Information
83789
Clinical Information
Iodine is an essential element required for thyroid hormone production. The measurement of iodine serves as an index of adequate dietary iodine intake and iodine overload, particularly from iodine-containing drugs, such as amiodarone.
Interpretation
Values between 80 ng/mL and 250 ng/mL have been reported to indicate hyperthyroidism.
Values above 250 ng/mL may indicate iodine overload.
Cautions
There are no known analytical interferences with this procedure.
Administration of iodine-containing contrast media will yield elevated results.
Report Available
1 to 4 daysSpecimen Retention Time
14 daysReject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
NY State Approved
YesMethod Name
Inductively Coupled Plasma Mass Spectrometry (ICP-MS)