Epic Test Code LAB2910 Phenosense Combination HIV Drug Resistance Assay
Additional Codes
MML:FPGT
Reporting Name
Phenosense GTPerforming Laboratory
Monogram Biosciences, IncSpecimen Type
Plasma EDTAOrdering Guidance
This procedure should be used for patients with documented HIV-1 infection and viral loads =500 copies/mL.
Specimen Required
Specimen Type: Plasma
Container/Tube: Lavender-top (EDTA) or plasma preparation tube (PPT)
Specimen Volume: 3 mL
Collection Instructions: Draw blood in either PPT (pearl top) or lavender-top (EDTA) tubes. Centrifuge specimen within six hours of collection. Remove plasma from cells immediately, and transfer specimen to a screw-capped, plastic vial. Freeze 3 mL of PPT plasma or EDTA plasma immediately, send specimen frozen.
To avoid delays in turnaround time when requesting multiple tests, please submit separate frozen specimens for each test requested.
RECOMMENDED:
1.    Patient's most recent viral load.
2.    Viral load collection date.
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NOTE:Â 1. Intended for use only for patients with viral loads greater than or equal to 500 copies/mL. For best results, viral loads should be confirmed within 2 weeks prior to submission for testing at Monogram.
           2. Patient samples submitted <30 days apart are considered duplicate and will be cancelled.
Specimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma EDTA | Frozen | 14 days |
Reference Values
A final report will be attached in MayoAccess.
Day(s) Performed
Sunday through Saturday
CPT Code Information
87900/Infectious agent drug susceptibility phenotype prediction
87901/Infectious agent genotype analysis by nucleic acid; reverse transcriptase and protease
87903/Infectious agent phenotype analysis by nucleic acid with drug resistance tissue culture analysis; first through 10 drugs tested
87904/x12 Each additional drug tested
Report Available
18 to 26 daysReject Due To
Other | PPT(TM) not centrifuged; quantity not sufficient for analysis; heparinized plasma; nonfrozen specimen; specimen exposed to repeated freeze/thaw cycles; specimen received in "pop-top" or "snap-cap" tube |
NY State Approved
YesMethod Name
Phenotype: polymerase chain reaction (PCR) amplification and viral culture; genotype: polymerase chain reaction (PCR) and DNA sequencing.
Useful For
Determines viral phenotype and genotype resistance to three classes of commonly prescribed antiretroviral drugs: nucleoside reverse transcriptase inhibitors (NRTI), nonnucleoside reverse transcriptase inhibitors (NNRTI), and protease inhibitors (PI). Viral replication capacity is also included.