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Epic Test Code LAB34 Salicylate

Performing Location(s)

BMC,CRH,LFH,OCH,FTT,FOX

Synonyms

Acetylsalicylic Acid, Aspirin

Specimen Type

Serum

Preferred Container

Gold Top

Alternate Container

Red Top

Blood Tube Draw Volume

Min 50% draw volume  

Minimum Volume to Submit for Testing

0.5 ml Serum

  • Multiple test can be performed from this volume. For question please contact the lab at 547-3975.  

Transportation Needs

 Deliver specimen to laboratory within 1 hour of collection if unspun. If not possible see "storage Requirements". 

Storage Requirements

Sample tubes should be centrifuged within 2 hour of collection followed by transfer of the serum (red or gold top)  to a labeled plastic, aliquot tube.

See Causes of Rejection for temperature requirements.

Causes for Rejection

Mislabeled or unlabeled specimen
Less than 50% draw for Vacutainer tubes
> 30 day Refigerated (Serum tubes are routinely stored at the lab for only 7 days therefore, an add-on may not be possible after 7 days.)
> 24 hours Room Temp
> 3 months Frozen

Hemolysis > 800 mg/dL HgB
Lipemia > 750 mg/dL Trig
Bilirubin > 30 mg/dL Bili

 

Reference Values

Population Units Reference Range High Critical Value
All populations mg/dl 2.8-20.0 >30

 

Limitations

Salicylate concentrations less than 2.8 mg/dL[0.20 mmol/L] should be considered negative (serum blank). At salicylates concentration of 20 and 40 mg/dL [1.45 and 2.90 mmol/L], salicyluric acid at 100 mg/dL increases the SAL result by 55%.

 

Days of Analysis

All

Available STAT

Yes

Additional Information

Therapeutic salicylate concentrations vary significantly, depending on the individual. A range of 2.8-20 mg/dL [0.20-1.45 mmol/L] includes effective serum concentrations for many patients; however, some individuals are best treated at concentrations outside this range.

 

Concentrations greater than 30 mg/dL[2.17 mmol/L] are often associated with toxic symptoms.

 

Concentrations greater than 60 mg/dL [4.34 mmol/L] are often lethal.

 

Should not be drawn earlier than 4 hours post ingestion. If time of ingestion is not known, two or more specimens drawn at 4 hour intervals may be used to estimate toxicity. The half-life of acetaminophen should be <4 hours. If two samples are drawn 4 hours apart, the second sample should be <50% of the first sample.

Drug Screen Assay Specificity.

Drug Screen Assay Interferences.

Methodology

Beckman AU/Dx Series

CPT Code

80329 (1 - 2 ordered)

80330 (3 - 5 ordered)

80331 (6 or more ordered)

Last Updated

18-Mar-22 KT