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Epic Test Code LAB3785 Histone Antibody, IgG

Additional Codes

ARUP: 0050860

Ordering Recommendation 

Evaluate suspected drug-induced lupus. Negative results do not rule out drug-induced lupus.

 

Histone antibodies are present in 20-55% of idiopathic systemic lupus erythematosus (SLE) and 80-95% of drug-induced SLE. They occur in less than 20% of other types of connective tissue diseases.

Preferred Container

Gold top tube

Specimen Type

Serum

Blood Tube Draw Volume

Min 50% draw volume  

Minumum Volume to Submit for Testing

1 mL Serum

  • Multiple test can be performed from this volume. For question please contact the lab at 547-3975.

Storage Requirements

Ambient: 48 hours
Refrigerated: 2 weeks
Frozen: 1 year (avoid repeated freeze/thaw cycles) 

Transporation Needs

Deliver specimen to the laboratory within 1 hour of collection. If not possible see “storage requirements”

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an Standard Transport Tube. And send refigerated

Cause of Rejection

Less than 50% draw for Vacutainer tubes
Mislabeled or unlabeled specimen
Plasma or urine.
Contaminated specimens.
Grossly hemolyzed,
icteric, 
lipemic specimens

 

Reference Value

0.9 units or less Negative
1.0-1.5 units Weak Positive
1.6-2.5 units Moderate Positive
2.6 units or greater Strong Positive

Days of Analysis

Mon, Wed-Sat

Turnaround Time

1-3 Days once specimen is recived into testing lab

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

CPT Code

83516

Last Updated

6-Dec-19