Sign in →

Browse by Name

  1. A
  2. B
  3. C
  4. D
  5. E
  6. F
  7. G
  8. H
  9. I
  10. J
  11. K
  12. L
  13. M
  14. N
  15. O
  16. P
  17. Q
  18. R
  19. S
  20. T
  21. U
  22. V
  23. W
  24. X
  25. Y
  26. Z
  27. #
 

Laboratory Contacts

Phone:

607-547-3975
607-547-3866
607-547-6722
Fax:
607-547-5438

Created by:

Benjamin Bascomb & Jamie Govern (2015)

____________________________________

 

Informational Links

Lab Departments

Lab Specific Documents

Informational Links for Providers

 

Patient Information

Documents and Forms

Pathology on Call Scheduled

Policies and Procedures

General Information

Top Reference Laboratory (In order to search)

  1. Mayo Clinical Labs
  2. ARUP Laboratories
  3. Quest Laboratories
  4. LabCorp

Mayo Clinic Laboratories

Epic Test Code LAB379 Cocaine and Metabolite Confirmation, Random, Urine

Additional Codes

MML:COKEU

Reporting Name

Cocaine and metabolite Conf, U

Useful For

Detecting and confirming drug abuse involving cocaine

 

This test is not intended for employment-related testing.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order COKEX / Cocaine and Metabolite Confirmation, Chain of Custody, Random, Urine.

2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.

3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.


Specimen Minimum Volume

5 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reference Values

Negative (Positive results are reported with a quantitative result.)

 

Cutoff concentrations by gas chromatography mass spectrometry:

Cocaine: 50 ng/mL

Benzoylecgonine: 50 ng/mL

CPT Code Information

80353

G0480 (if appropriate)

Clinical Information

Cocaine is a drug of current health concern because of its proliferation among recreational drug abusers.

 

Freebase and crack increase the potential for major cocaine toxicity. Cocaine use is declining across the nation according to the National Institute of Drug Abuse.

 

Increasingly, laboratory results are disputed or there are medical/legal overtones. Therefore, physicians are finding an increased need to confirm positive results before informing or confronting the patients.

Interpretation

Reports will specifically indicate the presence or absence of cocaine and benzoylecgonine.

 

The presence of cocaine, or its major metabolite, benzoylecgonine, indicates use within the past 4 days.

 

Cocaine has a 6-hour half-life, so it will be present in urine for 1 day after last use.

 

Benzoylecgonine has a half-life of 12 hours, so it will be detected in urine up to 4 days after last use.

 

There is no correlation between concentration and pharmacologic or toxic effects.

Cautions

No significant cautionary statements

Report Available

2 to 5 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

NY State Approved

Yes

Method Name

Gas Chromatography Mass Spectrometry (GC-MS) Confirmation with Quantitation

Day(s) Performed

Monday, Wednesday, Thursday, Friday

Specimen Retention Time

14 days

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.