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HelpEpic Test Code LAB3895 Trichinella Antibody, IgG, Serum
Additional Codes
MML:TRCNG
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Useful For
As an adjunct in the diagnosis of trichinosis
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Reporting Name
Trichinella Ab, IgG, SSpecimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 30 days | |
| Refrigerated | 5 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Heat-inactivated | Reject |
Clinical Information
Trichinosis is an infection by the nematode parasite, Trichinella spiralis. The infection is acquired by ingestion of larvae in inadequately cooked, contaminated meat, especially pork, bear, and walrus meat. After ingestion, acid-pepsin digestion in the stomach liberates the larvae, which develop into adult worms in the small intestine. After fertilization, the female worm produces larvae that penetrate the mucosa and seed the skeletal muscles via the blood stream. The larvae coil and encyst in muscle fibers, remaining viable for up to several years.
Diarrhea is the most common symptom associated with intestinal infection with adult worms. Fever, periorbital swelling, muscle pain and swelling, pulmonary symptoms, and rash develop during systemic invasion by the larvae.
Reference Values
Negative
Reference values apply to all ages.
Interpretation
Positive:
Results are suggestive of current or past infection with Trichinella spiralis. Results should be used in conjunction with clinical, epidemiologic and other laboratory tests to diagnose current infection.
Borderline:
Recommend follow-up testing in 10 to 14 days if clinically indicated
Negative:
No antibodies to Trichinella spiralis detected. Repeat testing in 2 to 3 weeks if clinically indicated.
Cautions
Antibodies to Trichinella spiralis may not be detectable until 3 weeks after the onset of infection. Therefore, negative results in suspicious cases should be followed by repeat testing in several weeks.
Sensitivity of the test may also be affected by the level of invasive disease, with patients who have lower parasitic loads having a greater risk of being negative by the assay.
Cross reactions with antibodies against Toxocara canis are possible.
Day(s) Performed
Thursday
Report Available
1 to 7 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86784
NY State Approved
YesForms
If not ordering electronically, complete, print, and send an Infectious Disease Serology Test Request (T916) with the specimen.