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Mayo Clinic Laboratories

Epic Test Code LAB4937 EGFR T790M Mutation Detection in Circulating Tumor DNA by Digital Droplet PCR

Additional Codes

ARUP: 2012868

Ordering Recommendation

Monitor for development of EGFR T790M drug-resistant mutation in patients administered tyrosine kinase inhibitor (TKI) therapy for EGFR-mutant non-small cell lung cancer. Monitor response to therapy and disease progression in patients treated with EGFR T790M-specific TKIs

Specimen Type

Whole blood in two 10mL Cell-Free DNA (cfDNA) BCT Tubes. Specimens must be collected using the kit

Volume Required

20 mL whole blood in cfDNA BCT Tubes

Minimum Volume

16 mL

Storage Requirements

Ambient: 5 days; Refrigerated: 5 days; Frozen: Unacceptable 

Transportation Needs

Refrigerated

Cause of Rejection

FFPE tissue. Whole blood collected in non-cfDNA BCT tubes

Turnaround Time

10-12 days

Methodology

Polymerase Chain Reaction

CPT Code

81235

Last Updated

14-Feb-17