Home
HelpEpic Test Code LAB494 RPR (Rapid Plasma Reagin) Monitoring/Pre-Employment
Performing Location(s)
OCH
Synonyms
Serological Test for Syphilis (STS)
Specimen Type
Serum
Preferred Container
Gold or Red top tube
Blood Tube Draw Volume
Min 50% draw volume
Minimum Volume to Submit for Testing
2 mL Serum
Storage Requirements
Sample tubes should be centrifuged within 2 hour of collection followed by transfer of the serum (red or gold top) to a labeled plastic, aliquot tube.
See Causes of Rejection for temperature requirements.
Transportation Needs
Deliver specimen to laboratory within 1 hour of collection if unspun. If not possible see "storage Requirements".
Causes for Rejection
Mislabeled or unlabeled specimen
Less than 50% draw for Vacutainer tubes
Wrong specimen container
Contaminated specimen
Hemoylsis ≥5+
Lipemia/Turbidity ≥ 4+
Serum > 5 days Refrigerated
Limitations
When result is Non-reactive: No laboratory evidence of syphilis infection. If recent exposure is suspected, re-draw specimen in 2-4 weeks and order RPR with reflex (LAB4941).
When result is Reactive: Non-treponmal antibodies detected. Syphilis infection unlikely; biologic false positive likely. Clinical evaluation should be performed to identify signs, symptoms or past history of infection. If recent exposure is suspected, re-draw specimen in 2-4 weeks and order RPR with reflex (LAB4941).
Reference Values
| Population | Units | Reference Range |
| All Populations | none | Non-Reactive |
Reflex Testing
When an RPR screen is reactive, a titer will be performed and billed.
Days of Analysis
M,W,F
Available STAT
No
Includes
Titer, if positive
Methodology
Charcoal agglutination
Additional Information
Additional Information:
A reactive RPR is a NYSDOH reportable communicable disease. The NYSDOH will be notified of all positive RPR’s.
This test is not available on a STAT basis.
CPT Code
86592 (also see reflex testing)
Last Updated
18-Mar-22 BHD