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Epic Test Code LAB4941 RPR (Rapid Plasma Reagin) with Reflex

Important Note

Screening Newborns (<30 days old)

Performing Location(s)

OCH

Synonyms

Serological Test for Syphilis (STS)

Specimen Type

Serum

Preferred Container

Gold or Red top tube

Blood Tube Draw Volume

Min 50% draw volume  

Minimum Volume to Submit for Testing

2 mL Serum

Storage Requirements

Sample tubes should be centrifuged within 2 hour of collection followed by transfer of the serum (red or gold top) to a labeled plastic, aliquot tube.
See Causes of Rejection for temperature requirements.

Transportation Needs

Deliver specimen to laboratory within 1 hour of collection if unspun. If not possible see "storage Requirements". 

Causes for Rejection

Mislabeled or unlabeled specimen
Less than 50% draw for Vacutainer tubes
Wrong specimen container
Contaminated specimen

Hemoylsis  ≥5+

Lipemia/Turbidity  ≥ 4+

Serum > 5 days Refrigerated

 

Limitations

When result is Non-reactive: No laboratory evidence of syphilis infection. If recent exposure is suspected, re-draw specimen in 2-4 weeks and order RPR with reflex (LAB4941).

 

When result is Reactive: Non-treponmal antibodies detected. Syphilis infection unlikely; biologic false positive likely. Clinical evaluation should be performed to identify signs, symptoms or past history of infection. If recent exposure is suspected, re-draw specimen in 2-4 weeks and order RPR with reflex (LAB4941).

Reference Values

Population Units Reference Range
All Populations none Non-Reactive

 

Reflex Testing

When an RPR screen is reactive, a titer will be performed and billed.

 

When an RPR screen is reactive, the specimen will be sent to the reference laboratory for confirmatory testing TP-PA (CPT: 86780)

 

 

Days of Analysis

M,W,F

Available STAT

No

Includes

Titer, if positive

Additional Information

Additional Information:

A reactive RPR is a NYSDOH reportable communicable disease. The NYSDOH will be notified of all positive RPR’s.

 

This test is not available on a STAT basis.

Methodology

Charcoal agglutination

CPT Code

86592 (also see reflex testing)

Last Updated

18-Mar-22 BHD