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Epic Test Code LAB496 Rubella Antibody

Performing Location(s)

BMC

Specimen Type

Serum

Preferred Container

Gold or Red top tube

Blood Tube Draw Volume

Min 50% draw volume  

Minimum Volume to Submit for Testing

1 mL Serum

  • Multiple test can be performed from this volume. For question please contact the lab at 547-3975.  

Transportation Needs

 Deliver specimen to laboratory within 1 hour of collection if unspun. If not possible see "storage Requirements". 

Storage Requirements

Sample tubes should be centrifuged within 2 hour of collection followed by transfer of the serum (red or gold top) to a labeled plastic, aliquot tube

Causes for Rejection

Mislabeled or unlabeled specimen
Less than 50% draw for Vacutainer tubes
> 48 hours refrigerated
>  8 hours room temperature
> 6 months Frozen
Hemolysis > 2000 mg/dL HgB
Lipemia > 1500 mg/dL Trig
Bilirubin > 20 mg/dL Bili

Limitations

Lipemic, hemolyzed, or icteric serum may interfere with the assay. See Causes for Rejection.

Specimens taken early during acute phase of infection may not contain detectable levels of IgG antibodies to the Rubella virus.

Among populations, the occurrence of IgG antibody to Rubella virus varies as does the level of seropositivity.

Reference Values

Result

Units

Interpretation

Positive

≥15.0 IU/mL

A Positive result is considered to be reactive for the presence of Rubella IgG antibodies and indicates acute or past infection or vaccination. The CDC Immunization Practices Advisory Committee opined that the presence of any detectable level of rubella IgG indicates immunity and protection against viremic infection.

Equivocal

10.0-14.9 IU/mL

An Equivocal result suggests that vaccinated individuals having these low levels of anti-rubella  IgG do show a secondary immune response following re-vaccination but have not been challenged with wild rubella virus. A follow-up sample should be taken to further evaluate immune status.

Negative

<10.0 IU/mL

A Negative result is considered non-reactive for the presence of rubella IgG antibodies. Patients with these results are considered to have an absence of immunity.

Days of Analysis

All

Available STAT

No

Additional Information

Additional Information:

This test is traceable to the WHO International Standard.

 

This test is not available on a STAT basis. If an emergency request is necessary, call 3731 for availability. Pathologist approval may be required.

 

A positive result indicates prior exposure and immunity to rubella or a convalescent stage of infection. The CDC Immunization Practices Advisory Committee opined that the presence of any detectable level of rubella IgG indicates immunity and protection against viremic infection.

Methodology

Beckman AU/Dx Series

CPT Code

86762

Last Updated

9-Nov-22 BHD