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Epic Test Code LAB798 Hepatitis A  Antibody IgM

Performing Location(s)

BMC

Synonyms

Antibody to Hepatitis A virus, IgM

Specimen Type

Serum

Preferred Container

Gold or Red top

Blood Tube Draw Volume

Min 50% draw volume  

Minimum Volume to Submit for Testing

2 mL Serum

Storage Requirements

Sample tubes should be centrifuged within 2 hours of collection followed by transfer of the serum (red or gold top) to a labeled plastic, aliquot tube and stored refrigerated.

See Causes of Rejection for temperature requirements.

Transportation Needs

Deliver specimen to laboratory within 1 hour of collection if unspun. If not possible see "storage Requirements". 

Causes for Rejection

Mislabeled or unlabeled specimen

Plasma

Spun or Unspun sample >7 days at 2-8 °C

Spun or Unspun sample >3 days at Room Temperature

Hemolysis > 500 mg/dL HgB
Lipemia > 3000 mg/dL Trig
Bilirubin > 20 mg/dL Bili
Total Protein >12 g/dL

Limitations

Specimens from patient who have received mouse monoclonal antibodies (HAMA) for diagnosis or therapy may exhibit either falsely elevated or depressed levels.

Hydrophobic antibodies in human serum may interfere, and additional info may be needed for specimens from patients with Non-Hodgkin’s Lymphoma.

Reference Values

Hepatitis A Antibody (IgM) Reference Range
Population Units Reference Range
All populations S/CO < 0.80 Negative

 

Includes

Qualititative analysis for Hepatitis A IgM Antibody.

Additional Information

This test is not available on a STAT basis or off-hours, weekends or holidays. If an emergency request is necessary, call 3731 for availability. Pathologist approval may be required.

 

Hepatitis Testing Guideline/Information

Days of Analysis

M-F only.

Interpretation

Negative result does not exclude exposure to Hepatitis A virus, as levels of IgM Anti HAV antibodies may be below the cut-off in early infection.

A positive HAV IgM result does not exclude co-infection by another hepatitis virus.

This test does not measure anti-HAV IgG and cannot be used to determine a patient's immune status to hepatitis A

Assay results cannot be considered quantitative and no clinical claims for immunity can be determined from the cutoff.    

Monitoring IgM Anti-HAV levels at 1 week intervals will distinguish rapidly rising antibody levels associated with early acute HAV infection from gradually decreasing or unchanging levels often associated with late acute stage infection.

Available STAT

No

Methodology

Two Step Chemilumimetric Immunoassay

CPT Code

Hepatitis A IgM AB: 86709

Last Updated

18-Mar-22 BHD