Epic Test Code LAB832 Cadmium, Blood
Additional Codes
MML Code: CDB
NY State Approved
YesPerforming Laboratory
Mayo Clinic Laboratories in RochesterReporting Name
Cadmium, B
Blood Tube Draw Volume
Min 50% draw volume
Method Name
Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Whole blood | Refrigerated (preferred) | 28 days | |
Ambient | 28 days | ||
Frozen | 28 days |
Specimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies: Metal Free B-D Tube (EDTA), 6 mL (T183)
Container/Tube: Royal blue top (EDTA) plastic trace element blood collection tube
Specimen Volume: Full tube
Collection Instructions:
1. See Metals Analysis Specimen Collection and Transport  for complete instructions.
2. Send whole blood specimen in original collection tube. Do not aliquot.
Specimen Type
Whole bloodSpecimen Minimum Volume
0.3 mL
Reference Values
<5.0 ng/mL
Reference values apply to all ages.
Report Available
1 to 2 daysDay(s) Performed
Monday through Saturday
CPT Code Information
82300
Reject Due To
Gross hemolysis | OK |
Gross lipemia | OK |
Gross icterus | OK |
Useful For
Detecting exposure to cadmium, a toxic heavy metal
Clinical Information
The toxicity of cadmium resembles the other heavy metals (arsenic, mercury, and lead) in that it attacks the kidney; kidney dysfunction with proteinuria with slow onset (over a period of years) is the typical presentation.
Breathing the fumes of cadmium vapors leads to nasal epithelial deterioration and pulmonary congestion resembling chronic emphysema.
The most common source of chronic exposure comes from spray painting organic-based paints without a protective breathing apparatus; auto repair mechanics represent a susceptible group for cadmium toxicity. In addition, another common source of cadmium exposure is tobacco smoke.
Interpretation
Normal blood cadmium is less than 5.0 ng/mL, with most results in the range of 0.5 to 2.0 ng/mL.
Acute toxicity will be observed when the blood level exceeds 50 ng/mL.
Cautions
No significant cautionary statements