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Epic Test Code Lab3779 Hepatitis A Antibody IgG

Performing Location(s)

BMC

Synonyms

Antibody to Hepatitis A virus, IgG

Specimen Type

Serum

Preferred Container

Gold or Red top

Minimum Volume to Submit for Testing

2 mL Serum

Storage Requirements

Sample tubes should be centrifuged within 2 hours of collection followed by transfer of the serum (red or gold top) to a labeled plastic, aliquot tube and stored refrigerated.

See Causes of Rejection for temperature requirements.

Transportation Needs

Deliver specimen to laboratory within 1 hour of collection if unspun. If not possible see "storage Requirements". 

Causes for Rejection

Mislabeled or unlabeled specimen

Plasma

Spun or Unspun sample >7 days at 2-8 °C

Spun or Unspun sample >3 days at Room Temperature
Hemolysis > 500 mg/dL HgB
Lipemia > 3000 mg/dL Trig
Bilirubin > 20 mg/dL Bili
Total Protein >12 g/dL

Limitations

Specimens from patient who have received mouse monoclonal antibodies (HAMA) for diagnosis or therapy may exhibit either falsely elevated or depressed levels.

Hydrophobic antibodies in human serum may interfere, and additional info may be needed for specimens from patients with Non-Hodgkin’s Lymphoma.

Reference Values

Hepatitis A Antibody (IgG) Reference Range
Population Units Reference Range
All populations S/CO  Negative

 

Available STAT

No

Days of Analysis

M-F only.

Additional Information

This test is not available on a STAT basis or off-hours, weekends or holidays. If an emergency request is necessary, call 3731 for availability. Pathologist approval may be required.

 

Hepatitis Testing Guideline/Information

Includes

Qualititative analysis for Hepatitis A IgG Antibody.

Methodology

Two Step Chemilumimetric Immunoassay

Interpretation

Negative result does not exclude exposure to Hepatitis A virus, as levels of IgG Anti HAV antibodies may be below the cut-off in early infection.

A positive HAV IgG result does not exclude co-infection by another hepatitis virus.

Assay results cannot be considered quantitative and no clinical claims for immunity can be determined from the cutoff.    

Monitoring IgM Anti-HAV levels at 1 week intervals will distinguish rapidly rising antibody levels associated with early acute HAV infection from gradually decreasing or unchanging levels often associated with late acute stage infection.

CPT Code

Hepatitis A IgG AB: 86708

Last Updated

18-Mar-22 BHD